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Search Results for " p 18 "

17

Compounds

2

Natural Products

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T33493 Mppf F-18 J1.050.795B,P-18FMPPF,(18F) Mppf,(18F)Mppf,(18F)-Mppf
Mppf F-18, which has been used as a radioactive ligand for positron emission tomography, is a compound that binds to the serotonin-1A receptor.
T62784 KRAS inhibitor-18
KRAS inhibitor-18 (compound 3-10) is a potent inhibitor of KRAS G12C (IC50: 4.74 μM). KRAS inhibitor-18 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 66.4, 11.1 μM respectively. KRAS inhibitor-18 has...
T80139 CRAMP-18 (mouse) Antibiotic
CRAMP-18 (mouse) is an antibiotic peptide with demonstrated efficacy against Gram-negative bacteria, including S. typhimurium and P. aeruginosa, while exhibiting no hemolytic activity. This compound shows promise for res...
T35574 Adenosine 5'-phosphosulfate (sodium salt)
Adenosine 5'-phosphosulfate is an ATP and sulfate competitive inhibitor of ATP sulfurylase in humans, S. cerevisiae, and P. chrysogenum (Ki = 18, 2500, and 1500 nM, respectively). Adenosine 5'-phosphosulfate also inhibit...
T83849 OP-145 TFA acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide,P60.4-Ac
OP-145, a derivative of the antimicrobial peptide LL-37, is a synthetic antimicrobial peptide showing activity against E. coli, P. aeruginosa, C. albicans, and A. niger, with minimum inhibitory concentrations (MICs) of 2...
T72416 Antimalarial agent 18
Antimalarial agent 18, a powerful antimalarial compound characterized by its electronic, highly lipophilic, and siderophoric properties, falls within the acyloxymethyl series, acting as a fosmidomycin surrogate. It effec...
T37455 C18 D-threo Ceramide (d18:1/18:0) C18 D-threo Ceramide (d18:1/18:0)
C18 D-threoCeramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2[Matreya, LLC. Catalog No. 1855] 1.Koola...
T35678 2,3-Indolobetulinic glycine amide
2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity. 1.Kumar, V., Rani, N., Aggarwal, ...
T14382 AZD7687 Others
AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial...
T35485 6-Prenylindole
6-Prenylindole is a bacterial metabolite that has been found in Streptomyces and has antifungal and antimalarial properties.1 It is active against A. brassicicola strain TP-F0423 and F. oxysporum f. sp. tulipae TU-4-2 (1...
T35494 (±)11(12)-EET
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms C...
T36021 Flumequine-13C3 Flumequine-13C3
Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. col...
T37832 CAY10761 CAY10761
CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) an...
T36629 Givinostat
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30...
T36215 17R(18S)-EpETE
17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium curren...
T36521 Alaproclate (hydrochloride)
Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s =...
T36012 p38α inhibitor 2
P38α Inhibitor 2, a potent and selective inhibitor of p38α MAPK, exhibits a pIC50 value of 9.6. It also demonstrates inhibition of the hERG ion channel (IC50=27 μM) and maintains promising selectivity, with <30% inhibiti...
Cat No. Product Name Synonyms Targets
T37690 Phenylpyropene A
Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM)....
T35624 Ajoene
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02608 UBC9/UBE2I Protein, Human, Recombinant Human E. coli
UBE2I is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed ...
TMPY-03976 EEF1E1 Protein, Human, Recombinant (His) Human E. coli
EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex...
TMPY-04110 TPPP2 Protein, Human, Recombinant (His) Human E. coli
TPPP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.3 kDa and the accession number is AAH38970.1.
TMPH-01181 CYP11B2 Protein, Human, Recombinant (His & SUMO) Human E. coli
CYP11B2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-01820 Munc18-1/STXBP1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Syntaxin-binding protein 1, also known as N-Sec1, Protein unc-18 homolog 1, MUNC18-1 and STXBP1, is a peripheral membrane protein that belongs to the STXBP / unc-18 / SEC1 family. STXBP1 is an evolutionally conserved neu...
TMPJ-00640 CTLA-4 Protein, Cavia porcellus, Recombinant (His) Cavia porcellus P. pastoris (Yeast)
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1.
TargetMol